“Just because we can, doesn’t mean we should , and if we do, let’s do it well.”

The rise of GLP-1 receptor agonists like semaglutide and liraglutide marks a powerful new era in metabolic and preventive medicine. These medications offer much more than weight loss:

✅ Improved glycaemic control in type 2 diabetes

✅ Reduction in cardiovascular risk (MI, stroke)

✅ Reversal of fatty liver (NAFLD/NASH)

✅ Improved insulin resistance, especially in PCOS

✅ Neuroprotective potential in Alzheimer’s and Parkinson’s

✅ Reduction in compulsive behaviours (binge eating, alcohol, smoking)

✅ Reduced systemic inflammation and improved quality of life

But as with any powerful tool, their misuse carries risks.

We are now witnessing:

⚠️ Rapid, unsupervised weight loss

⚠️ Excessive fat and muscle depletion

⚠️ “Ozempic face” and a surge in laxity and gauntness

⚠️ A worrying shift in body image standards, fuelled by influencers and unregulated access

GLP-1s are not lifestyle replacements or aesthetic shortcuts.

They are medical therapies that should be prescribed with care, context, and clinical oversight — ideally as part of a comprehensive plan that includes nutrition, movement, and mental health support.

At AAMSSA, we advocate for:

🧠 Responsible prescribing

🩺 Evidence-based use

👩‍⚕️ Individualised dosing (including microdosing where appropriate)

📉 Gradual weight loss with ongoing monitoring

💡 Patient education on risks, benefits, and stopping points

GLP-1s hold enormous potential but it’s up to us, as medical professionals, to guide their use ethically, safely, and with long-term health in mind.